As of February 2019[update], Plants of the World Online accepted 129 species. Between 65 and 300 species have been recognised at various times, depending on the circumscription of the genus. There are no clinical data regarding the use of P. multiflorum in cancer. Polygonum multiflorum, Helxine multiflorum, Pleuroptterus cordatus, Polygonum convolvulus, Polygonum multiflorus Common Names Chinese Knotweed, Climbing Knotweed, Fo ti, Flowery Knotweed, He-Shou-Wu, Kashuu (He Shou Wu in Chinese pinyin, hereinafter referred to as HSW) is the root ofPolygonum multiflorum, a member of Polygonaceae. Suitable pH: acid, neutral and basic (alkaline) soils. by Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland, Oregon. : 823837 (Download Help) Polygonum multiflorum TSN 823837 Taxonomy and Nomenclature Kingdom: Plantae : Taxonomic Rank: Species : Common Name(s): tuber fleeceflower [English] Accepted Name(s): Fallopia multiflora (Thunb.) P. multiflorum and its extracts should be considered hepatotoxic; however, the plant is widely used in traditional Chinese medicine and Ayurvedic medicine for its rejuvenating and toning properties, to increase liver and kidney function, for treatment of cognitive disorders and dyslipidemia, and to cleanse the blood. P. multiflorum is native to central and southern China and is also distributed in Japan and Taiwan. General Information Polygonum multiflorum is a Perennial Climber up to 4.50 metres tall. P. multiflorum is widely used in Chinese medicine; however, adverse event reporting under clinical trial conditions is lacking. They are longish-elliptical with short stalks and rounded bases ; … 8.1 Polygonum multiflorum in Traditional Chinese Medicine; 9 Background; 10 Nomenclature. [2], The genus Polygonum was first described by Carl Linnaeus in 1754. Description Polygonatum multiflorum is a rhizomatous perennial that grows up to 3 feet (90 cm) tall and up to 10 inches (25 cm) wide, with alternate leaves on arching stems. It cannot grow in the shade. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Ho-shou-wu (pinyin: heshouwu) is derived from the roots of Polygonum multiflorum.The herb was first recorded (1,2,16) in the Ri Huazi Bencao (Tang Dynasty, 713 A.D.) and then incorporated into the well-known Kaibao Bencao (Song Dynasty; 973 A.D.). Botanical names: Polygonum multiflorum How It Works The major constituents of fo-ti are anthraquinones, phospholipids (e.g., lecithin), tannins, and tetrahydroxystilbene glucoside. hypoleucum, Fallopia multiflorum var. Polygonum is a genus in the Polygonaceae family. Raw, wine- or steam-processed, or cured fo-ti is available in the United States.1, 2, 3, 4, Radix Polygoni multiflori or he shou wu is a popular Chinese tonic herb, whose usage dates back to 713 AD.2 Fo-ti appears to be a name given to the preparation for use in areas where Chinese is not the primary language.4 It is considered one of the country's great 4 herbal tonics, along with angelica, lycium, and panax, and is used to increase liver and kidney function and to cleanse the blood.3 The plant is also prescribed for symptoms of premature aging, such as gray hair, and is commonly found in hair care products in China.2, 4 It is also used to treat insomnia, weak bones, constipation, and atherosclerosis.2 Regarded as a rejuvenating plant, fo-ti has been thought to prevent aging and promote longevity. Taxonomic Serial No. You should talk with your health care provider for complete information about the risks and benefits of using this product. hypoleucum, syn. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. There are no clinical data regarding the use of P. multiflorum in alopecia or hair coloring despite widespread traditional use in China for this purpose. [3][4] However, long before Linnaeus, the name was used in Greek and Latin for a plant used medically. Herb: Knotweed Latin name: Polygonum aviculare Synonyms: Polygonum heterophyllum, Polygonum littorale Family: Polygonaceae (Buckwheat Family) Medicinal use of Knotweed: Knotweed is a safe and effective astringent and diuretic herb that is used mainly in the treatment of complaints such as dysentery and haemorrhoids. Radix Polygoni multiflori or he shou wu is a popular Chinese tonic herb, whose usage dates back to 713 AD.2 Fo-ti appears to be a name given to the preparation for use in areas where Chinese is not the primary language.4 It is considered one of the country's great 4 herbal tonics, along with angelica, lycium, and panax, and is used to increase liver and kidney function and to cleanse the blood.3 The plant is also prescribed for symptoms of premature aging, such as gray hair, and is commonly found in hair care pro… This product may be unsafe when used before surgery or other medical procedures. He Shou Wu is a Chinese herbal medicine, derived from the Polygonum multiflorum Thunb plant ().. The flowers are slightly necked, pendent, tubular, white, with green tips, hanging from the undersides of the stems. Plant Description: Chinese knotweed is a herbaceous vine, which quickly spreads and covers any available surfaces. The processed (cured) root of the plant is used to make medicine. 1 Fleeceflower root is widely produced across China, including in the Henan, Hubei, Guizhou, provinces. The species name multiflorum refers to the flowers. Polygonum L. – knotweed Species: Polygonum multiflorum Thunb. In the Middle English glossary of herbs Alphita (c. 1400-1425), it was known as ars-smerte. In vitro studies and limited animal data suggest P. multiflorum extracts, tetrahydroxystilbene glucoside and emodin, possess anticancer properties.5, 12, 23, 24 The focus of research into antiapoptotic activity centers on neuroprotection against degenerative disease (see CNS). Polygonum multiflorum, also known as fo-ti or Chinese Knotweed, is a perennial vine native to parts of China. It is a perennial climbing herb that can grow to 9 m in height. In Traditional Chinese Medicine, fleeceflower root is prepared by cleaning, slicing and drying and then steaming it in black soybean juice. Most species are considered weedy, especially in moist soils in the USA. There are usually four to six stamens and three (rarely two) styles. The idea of such use was also known to Shakespeare, as Beatrice K. Otto pointed out, quoting A Midsummer Night's Dream:[15]. 'fecund', 'with many offspring'. Fo-Ti is believed to als… This is only a brief summary of general information about this product. Common Name: He Shou Wu. It is probably best known for it’s ability to turn grey hair dark again. * The roots are the main plant part of interest and are harvested and dried in autumn when they are 3 to 4 years of age, but the stems and leaves are also used. Prepare as a tea or tonic, or as directed by a physician. Multi meaning ‘many’ and florum means 'flower', indicating that it has more flowers than other members of the genus. [6], Many members of the family Polygonaceae that are now placed in separate genera were at one time or other placed in Polygonum, including species of Fagopyrum, Fallopia, Persicaria and Reynoutria,[7] and older sources frequently use much wider definitions of the genus. Polygonum multiflorum Thunb. Last updated on Dec 12, 2019. Of page the name Polygonum aviculare knotgrass herb tea is pleasant for centuries, Polygonum multiflorum has used! Net Weight :250g. Hepatotoxicity has been documented.50, 51, 52 GI symptoms, including diarrhea, may be due to consuming raw or improperly processed fo-ti.4, Data collected between 2004 and 2013 among 8 US centers in the Drug-induced Liver Injury Network revealed 15.5% (130) of hepatotoxicity cases was caused by herbals and dietary supplements whereas 85% (709) were related to medications. Molecular phylogenetic studies, particularly in the 21st century, have led to major changes. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Planta Med 2010;76(9):889-92. Directions: To use as a tea, pour 1 cup boiling water over 1 tsp. Former genera such as Polygonella have been subsumed into Polygonum; other genera have been split off. Polygonum multiflorum var. The Plants Database includes the following 83 species of Polygonum . Available for Android and iOS devices. [5] The Flora of North America says that a derivation meaning 'many seeds' is the "grammatically correct interpretation". Discussing the plant he knew as polygonum in 1655, Matthias Martinius referred to Scribonius Largus (who wrote a list of prescriptions around 47 AD) and gave an alternative etymology, based on γόνος (gonos, 'offspring', 'seed'), the meaning of the name then being the Latin foecundus, i.e. The species are very diverse, ranging from prostrate herbaceous annual plants to erect herbaceous perennial plants. The species is hermaphrodite (has both male and female organs). A number of species that had been included in Polygonum have been moved into several other genera, including Bistorta, Fagopyrum, Fallopia, Koenigia, Persicaria and Reynoutria. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. The species Polygonatum multiflorum is often called the Common Solomon's Seal, native to Europe it has been long cultivated for its use as a medicinal herb. Click below on a thumbnail map or name for species profiles. 5.1 Polygonum multiflorum in Traditional Chinese Medicine; 6 Background; 7 Nomenclature. This information should not be used to decide whether or not to take this product. In vitro studies in tissues of the CNS report decreased neuroinflammation via inhibition of microglia activation,30 promotion of hippocampal synaptic plasticity,31 antioxidant effect in hippocampal and other cells,32, 33, 34, 35 and the reduction of amyloid peptide production.36 In contrast, an in vitro study using cultured mouse cortical neurons showed an extract of P. multiflorum to be neurotoxic.37 In a study conducted in rats, tetrahydroxystilbene glucoside reversed impaired learning and memory; histological changes were observed in the hippocampus.38, P. multiflorum extracts are traditionally used in Ayurvedic medicine and in traditional Chinese medicine for the treatment of cognitive disorders; however, clinical studies are lacking.37 One study conducted among patients with Alzheimer disease (N = 209) reported that the extract was effective; details of the methodology are unclear.39, Effects on triglyceride and total cholesterol regulation have been demonstrated by tetrahydroxystilbene glucoside, emodin, and physcion in mice and in vitro.40, 41, 42, 43 Raw fo-ti appeared to be more effective than processed fo-ti in 1 study.41, There are no clinical data regarding the use of P. multiflorum in dyslipidemia; however, both raw and cured fo-ti are used in traditional Chinese medicine for dyslipidemia.4, In vitro studies have shown that extracts of P. multiflorum possess antioxidant properties.30, 35, 37, 44, 45, 46, 47, 48 Immunomodulatory and anti-inflammatory effects have also been reported.5 Reduction in the production of glycation end products in diabetes has been demonstrated in vitro.49, In contrast to the known hepatotoxicity of P. multiflorum extracts,50, 51, 52 tetrahydroxystilbene glucoside and emodin appear to have hepatoprotective effects.30, 32, 43, 48, P. multiflorum is used at daily doses of 9 to 15 g of raw herb, but clinical studies are lacking. Common Name: Fo-ti. 5 Historical Use of Polygonum multiflorum. More than 100 chemical compounds have been identified, and analytical techniques are described.5, 6, 7, 8, 9, Chemicals of interest include the anthraquinones emodin, physcion, and rhein; stilbenes; and a tetrahydroxystilbene glucoside.7, 10, 11, 12 Minerals and vitamins in the root have also been described.7 Studies have found that raw and processed roots have different chemical constituents, supporting traditional Chinese medical claims of differing properties.5, 13, 14, Extracts of P. multiflorum are not commonly used alone, but rather in combination with other herbs,5 including Buyangahuanw Pill Jiajian Fang and Qishu decoction. P. multiflorum is used at daily doses of 9 to 15 g of raw herb, but clinical studies are lacking. The plant may also be nephro-, neuro-, and embryotoxic. In the Middle English glossary of herbs Alphita (c. 1400–1425), it was known as ars-smerte. This is especially helpful to older people. A standard dose in the Chinese Pharmacopoeia is 3 to 12 g/day. Fallopia multiflora (Thunb.) J Ethnopharmacol 2006;104:144-8. Common name(s): Solomon’s Seal, David’s Harp, Ladder-to-Heaven Synonyme(s): N/A Family: Asparagaceae, Nolinoideae subfamily Origin: Asia (Caucasus, Nepal, Turkey), Europe More infos: A variegated cultivar is available. Polygonum multiflorum Thunb. Evidence exists of hepatic injury in humans. There have been various opinions about how broadly the genus should be defined. – tuber fleeceflower One more dish based on "madimak" polygonum cognatum: "Archival data on wild food plants used in Poland in 1948", https://www.youtube.com/watch?v=DzNCO94rWXE, https://www.youtube.com/watch?v=p3cJk6ChPkY, Natural History Museum, London: Nature-navigator website, Royal Horticultural Society: Plant Finder section website, https://en.wikipedia.org/w/index.php?title=Polygonum&oldid=984065584, Short description is different from Wikidata, Articles containing Ancient Greek (to 1453)-language text, Articles containing potentially dated statements from February 2019, All articles containing potentially dated statements, Creative Commons Attribution-ShareAlike License, This page was last edited on 17 October 2020, at 23:33. Protective effect of Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 induced cognitive deficits in mice. Some synonyms are listed below.[10]. It is in flower from July to September. The flowers are usually bisexual, rarely unisexual, and have five (occasionally four) tepals, the outer being slightly different from the inner ones. We comply with the HONcode standard for trustworthy health information -. Care should be taken not to confuse Polygonum with Polygonatum – an entirely different genus of plants. 10.1 Other Names: 11 Historical Use of Polygonum multiflorum. The plant is self-fertile. The fruit is three-sided. Species on this page ( A = names approved by most authorities, s = approved as synonyms) : Polygonum affine D. Don s -> Fallopia aubertii (L. Henry) Holub A; Polygonum amphibium L. -> Persicaria amphibia (L.) Gray; Polygonum amplexicaule D. Don; Polygonum aubertii L. Henry s-> Fallopia aubertii (L. Henry) Holub A Directions. There are no clinical data regarding the use of P. multiflorum in cardiovascular-related disorders. Used at daily doses of 9 to 15 g of raw herb but... 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